Rodney JY Ho

Biology


Location
United States
Gender
Male
Also Known As
Professor; Exec. Dir.—WE-REACH*; Dir.—TLC- ART†; Affiliate Member of Fred Hutch; Affiliate Faculty, CFAR^; Member of ITHS‡

Dr. Ho is a professor and presidential entrepreneurial fellow of the University of Washington, and holds appointments at the Fred Hutchinson Cancer Research Center. He is also an expert on pharmacology and systems approaches to drug targeting and long-acting therapy. His research aims to improve the therapeutic efficacy and safety of viral and cancer drugs, medical diagnostic agents and vaccines. He is an elected fellow of the American Association for the Advancement of Science (AAAS) and the American Association of Pharmaceutical Scientists (AAPS). He studies the relationships between drug target distribution and disease development in cancer, AIDS, and neurological disorders. Building on this understanding, he has developed a systems approach to drug delivery and targeting. He is known for his expertise in bio-therapeutics, lipid-drug and -protein interactions, liposomes, drug-combination nanoparticles, pharmacokinetics, and the interplay between tissue targets and drug penetration. His research has led to enhanced HIV, cancer, and pain medication potency and safety. In addition, he is an editor of the Journal of Pharmaceutical Sciences and the author of “Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs.” He has also received top honors including the Paul Dawson Biotechnology life-time achievement award and the AAPS Biotechnology Research achievement, one of the AAPS’s highest recognitions. Dr. Ho is known for biotechnology and nanotechnology research and education that enable transformation of basic biomedical discovery into therapeutics. In addition to innovations in drug formulations, his research focuses on biology and treatments of cancer and viral infectious diseases. Some topics include (1) Systems approaches to drug and protein transport, delivery, and drug targeting to improve efficacy and safety; (2) Drug-interaction and the genetic basis of inter-individual variations in AIDS and cancer therapies; (3) Drug and lipid or biomaterial interaction studies that enable the engineering and development of long acting and targeted systems that enhance drug potency and safety. http://depts.washington.edu/tlcart/

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